Neurodegenerative Disorders

Neurodegenerative disorders are defined by the progressive decline of neuronal functions in a spatiotemporal fashion, which leads to intensifying neurological symptoms, in some cases, with devastating speed. This is accompanied by the steady intensity of neuropathological findings from more to less affected regions in the nervous system. The molecular pathway driving constant decline of disease symptoms and pathology is not yet understood. However, the enlargement of pathological protein assemblies, spreading from cell-to-cell, may well explain these phenomena.

We will bring neurologists and   neuropathologists basic scientists from a wide variety of neurodegenerative diseases to discuss the conclusion of these mechanisms for building disease models and therapeutic strategies. We will also speak about the similarities and differences between the different classes of neurodegeneration, comparing to prototypical prion diseases.

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